Kildle Application for PC, how accessible is it?

Hi guys,
In late 2012, I recently started a new podcast. You may go over to the Books Podcast web site to learn more. It leads me to a question which people may comment on here if you wish, or send me an E-mail directly at tech at menvi.org putting the at symbol where it belongs. The question deals with the Kindle application for PC which I saw while looking around amazon. How accessible is this application for Windows? Would I be able to use Window-Eyes on it, or possibly NVDA? I’m sort of curious on peoples results.